NationStates Jolt Archive

Our country's "Citizen Entertainment" Agency is in need of moldy, rye bread in order to faciliate their operations. We are willing to pay as much as $0.0122 per slice for the bread. Please contact us if you can offer it for that or a lesser price (we would prefer to buy in bulk).

Sincerely,
Ruler for Life
Lysergicassid,
Dyethylamide

We'll give you real bread, for a quarter, in total.

We'll give you real bread, for a quarter, in total.

How much bread do we get for the quarter and please note, it MUST be rye bread capable of supporting the Ergot fungus.

You get all you need for a quarter >.>

My country can manufacture simple foods like rye bread. You get weight in bread as much as you supply in Carbon to us. We don't accept or use other country's currency or terms described in such. However, give us Carbon, we give you bread, deal?

Dobbs Town needs frop. And lots of it. Our central bakery is located in a deep, dark, moist jungle area and we've had a bumper crop of rye grain this year, due to a clerical error at the Ministry of Agriculture. Let our loss be your gain. All we ask for in return are as many bushels of frop as your carrier-pigeons can reasonably deliver before the harvest.

My country can manufacture simple foods like rye bread. You get weight in bread as much as you supply in Carbon to us. We don't accept or use other country's currency or terms described in such. However, give us Carbon, we give you bread, deal?

Deal, 300 tons is on its way.

Dobbs Town needs frop. And lots of it. Our central bakery is located in a deep, dark, moist jungle area and we've had a bumper crop of rye grain this year, due to a clerical error at the Ministry of Agriculture. Let our loss be your gain. All we ask for in return are as many bushels of frop as your carrier-pigeons can reasonably deliver before the harvest.

Deal, the pigeons are on their way

You get all you need for a quarter >.>

The quarter has been wired, please send us the largest shipment you can manage at this time to be followed by one more in the next 2 weeks.

Uhh, well can't help with the bread but we have a couple of old vats used to make cheese about 15 years ago that might help a bit. But you'll have to pick them up yourself if you want them. Noone living here is touching them with a 50ft crane.

How much bread do we get for the quarter and please note, it MUST be rye bread capable of supporting the Ergot fungus.

We are suspicious of your motives with respect to the production of Ergot.

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Ergot is a fungus that lives on rye and other grasses and is pathogenic to its host as well as to humans and other animals that ingest it. Ergot is also a great source for the art of healing and the pharmaceutical industry.

Like most great pharmacological resources, ergot is a powerful poison. More specifically, many ergot alkaloids have a poisonous effect on the central nervous system, interfering heavily with neurotransmitter function. And here also lies the great promise of ergot as medicine.

Ergot is an old member of the materia medica. It has been used in traditional medicine and it has been scientifically studied for more than 50 years. Among those studying ergot and its derivatives was the Swiss chemist Albert Hofman whose experiments let to the discovery of LSD, an ergot derivative that strongly interferes with the neurotransmitter serotonin.


In the field of conventional medicine, ergot derivatives are nowadays mostly used for their potential to enhance another neurotransmitter, dopamine. A dopamine deficiency is a common grave medical condition, known as Parkinson's Disease.



While the ergot derivative LSD issued almost exclusively as recreational drug with practically no use in conventional medicine, dopamine enhancing ergot derivatives are sold in pharmacies around the world. The most common ergot prescription drug is probably Sandoz' Parlodel (bromocriptine by generic name). Even though it's very much a conventional medication, bromocriptine and other dopamine enhancing ergot derivatives have a clear potential as life-style drugs. Not all, but many ergot-based parkinsonism medications have a profound sexuality enhancing (side) effect.

All dopamine-enhancing medications can be used in the treatment of parkinsonism, but not each and every dopamine enhancement produces pro-sexual (side) effects. On a similar level, while many medications used for serotonin enhancement (in the treatment of clinical depression) have anti-sexual effect, this anti-sexual effect is not an unavoidable side effect of serotonin enhancement.


The answer to the puzzle lies in dopamine and serotonin receptor sites. Not all dopamines and all serotonins are alike. The effect of some dopamine binding to specific sites is pro-sexual, and the binding of some other dopamines to other sites may be neutral at best, or even anti-sexual. The same holds true for serotonin enhancing drugs and serotonin binding sites.


Until now, many ergot derivatives are considered "dirty" drug. They are named like this because their action is not all too specific. They have the therapeutic effect for which they are prescribed, but they have many other effects, too. From the perspective of conventional medicine, the pro-sexual effects are a side effect

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:p