NationStates Jolt Archive

So I used to give blood, in fact for 20 years I have done this.

Last year though after a years gap(we have to wait a year after each
tattoo) I went back, gave my pint, and three weeks later received a
letter from the blood people thanking me for all of my donations over
the years and informing me that I am no longer able to give blood due
to the Anti-E Antibodies now present in my blood.

I was told that many people who have had a blood transfusion may in
time develop these anti bodies, and it seems that time has played a
cruel trick on me as it was almost 30 years ago that I had such a
transfusion.

Now I don't like not knowing things, but I don't know what Anti-E
Antibodies are, nor what they do, and so why I can no longer donate
blood. I wish to know, can anybody help?

So I used to give blood, in fact for 20 years I have done this.

Last year though after a years gap(we have to wait a year after each
tattoo) I went back, gave my pint, and three weeks later received a
letter from the blood people thanking me for all of my donations over
the years and informing me that I am no longer able to give blood due
to the Anti-E Antibodies now present in my blood.

I was told that many people who have had a blood transfusion may in
time develop these anti bodies, and it seems that time has played a
cruel trick on me as it was almost 30 years ago that I had such a
transfusion.

Now I don't like not knowing things, but I don't know what Anti-E
Antibodies are, nor what they do, and so why I can no longer donate
blood. I wish to know, can anybody help?

After a quick google search I have to ask.

Are you pregnant?

Heh hardly, I'm a man!

After a quick google search I have to ask.

Are you pregnant?

On a more serious note. It appears to have something to do with the Rhesus blood group (wiki (http://en.wikipedia.org/wiki/Rhesus_blood_group_system))

Anti-E Antibodies are a mechanism which develops typically in either pregnancies or in blood transfusions where the are some mismatched genetic material differentiation between the mixing blood from the Rh gene, which has 5 antigens labeled A,B,C,D,E. Anti-E occurs when the gene's are an Rh E- encountering an Rh E+ the antibodies develop which will start attacking the "foreign" blood cells (this can be hazardous to babies in pregnancies, and also can be hazardous if anyone receives blood containing the antibody, as this will "program" the hosts systems to attack its own red blood cells).

On a more serious note. It appears to have something to do with the Rhesus blood group (wiki (http://en.wikipedia.org/wiki/Rhesus_blood_group_system))

Yeah, I am an O rh+ with something about R1R1, which I have been told means that my blood went right to the SCBU(Special care baby unit) But I want to what anti-e antibodies do so that it means I can no longer give blood.

Yeah, I am an O rh+ with something about R1R1, which I have been told means that my blood went right to the SCBU(Special care baby unit) But I want to what anti-e antibodies do so that it means I can no longer give blood.

Have you noticed an increasing desire to gorge yourself on human brains?

Anti-E Antibodies are a mechanism which develops typically in either pregnancies or in blood transfusions where the are some mismatched genetic material differentiation between the mixing blood from the Rh gene, which has 5 antigens labeled A,B,C,D,E. Anti-E occurs when the gene's are an Rh E- encountering an Rh E+ the antibodies develop which will start attacking the "foreign" blood cells (this can be hazardous to babies in pregnancies, and also can be hazardous if anyone receives blood containing the antibody, as this will "program" the hosts systems to attack its own red blood cells).

Ahhhh then that makes sense, so because my blood is Rh+ it means that I have either the a, b, c, d, or e antigen? In this case I guess E? But hold on doesn't Rh- mean no rhesus, so Rh-E seems to me wrong? Or am I wrong?

Have you noticed an increasing desire to gorge yourself on human brains?

Umm not recent....errrr no.

Ahhhh then that makes sense, so because my blood is Rh+ it means that I have either the a, b, c, d, or e antigen? In this case I guess E? But hold on doesn't Rh- mean no rhesus, so Rh-E seems to me wrong? Or am I wrong?

The "+" is the Rh blood type refers to the "D" antigen in the gene, you're probably E- in the Rh gene, and were given E+ in a transfusion, causing your blood to build up Anti-E antibodies to fight the foreign blood cells.

The "+" is the Rh blood type refers to the "D" antigen in the gene, you're probably E- in the Rh gene, and were given E+ in a transfusion, causing your blood to build up Anti-E antibodies to fight the foreign blood cells.

do you know a lot about this stuff? I mean because you sound like you do, and I have a question.

The "+" is the Rh blood type refers to the "D" antigen in the gene, you're probably E- in the Rh gene, and were given E+ in a transfusion, causing your blood to build up Anti-E antibodies to fight the foreign blood cells.

Ahh okay yeah that makes more sense. Cheers.

In a woman, if she is one type and here husband is another type she can develop these anti's. Usually the first baby is ok, but if she has a second baby that also takes after the man's blood, the body can see the baby as a foreign object and reject it. So if the blood is given to a woman, any babies she has could be rejected, even the first.

Now how would this happen in a man? I don't know, but the best bet is a dirty needle when you got the tattoo (this is a wild guess) .

In a woman, if she is one type and here husband is another type she can develop these anti's. Usually the first baby is ok, but if she has a second baby that also takes after the man's blood, the body can see the baby as a foreign object and reject it. So if the blood is given to a woman, any babies she has could be rejected, even the first.

Now how would this happen in a man? I don't know, but the best bet is a dirty needle when you got the tattoo (this is a wild guess) .

This is probably valid, if the person performing the tattoo didn't properly sterilize the needle between uses.

i can't give blood because i take drugs and i have sex with men and i'm honest. so, fuck knows.

So I used to give blood, in fact for 20 years I have done this.

Last year though after a years gap(we have to wait a year after each
tattoo) I went back, gave my pint, and three weeks later received a
letter from the blood people thanking me for all of my donations over
the years and informing me that I am no longer able to give blood due
to the Anti-E Antibodies now present in my blood.

I was told that many people who have had a blood transfusion may in
time develop these anti bodies, and it seems that time has played a
cruel trick on me as it was almost 30 years ago that I had such a
transfusion.

Now I don't like not knowing things, but I don't know what Anti-E
Antibodies are, nor what they do, and so why I can no longer donate
blood. I wish to know, can anybody help?

I've never heard of it myself. I'm not in the mood to search it but could it due with Vitamin E ?