NationStates Jolt Archive


Mice Created With Human Brain Cells

Dishonorable Scum
13-12-2005, 16:39
Today's issue of Mad Scientist News is brought to you by the NationStates Academy of Mad Science

SAN FRANCISCO - Add another creation to the strange scientific menagerie where animal species are being mixed together in ever more exotic combinations. Scientists announced Monday that they had created mice with small amounts of human brain cells in an effort to make realistic models of neurological disorders such as Parkinson's disease.

Led by Fred Gage of the Salk Institute in San Diego, the researchers created the mice by injecting about 100,000 human embryonic stem cells per mouse into the brains of 14-day-old rodent embryos.

Those mice were each born with about 0.1 percent of human cells in each of their heads, a trace amount that doesn't remotely come close to "humanizing" the rodents.

"This illustrate that injecting human stem cells into mouse brains doesn't restructure the brain," Gage said.

Still, the work adds to the growing ethical concerns of mixing human and animal cells when it comes to stem cell and cloning research. After all, mice are 97.5 percent genetically identical to humans.

"The worry is if you humanize them too much you cross certain boundaries," said David Magnus, director of the Stanford Medical Center for Biomedical Ethics. "But I don't think this research comes even close to that."
Full article: http://news.yahoo.com/s/ap/20051213/ap_on_sc/mice_human_brains

Interesting... So what would be the implications if these mice showed enhanced cognitive ability, even if it didn't come remotely close to human intelligence?

:p
Gauthier
13-12-2005, 16:42
"So what are we going to do tonight Brain?"
"The same thing we do every night Pinky: Try to TAKE OVER THE WORLD!!"
The Blaatschapen
13-12-2005, 16:50
You do know that mice are actually the smartest organisms on this planet? :D

So we actually made them dumber now.
Safalra
13-12-2005, 17:01
Interesting... So what would be the implications if these mice showed enhanced cognitive ability, even if it didn't come remotely close to human intelligence?
I doubt it would happen, as it's the structure of the brain that corresponds to intelligence, not the nature of the neurones. Besides, most univeristy ethic boards have procedures in place to deal with part-human chimeras (the guidance is usually 'destroy it the moment it shows signs of greater intelligence').
Stelleriana
13-12-2005, 17:39
What do we do when they climb out of the cage and announce that they're going to temple/church/mosque and they'll be back later?
The South Islands
13-12-2005, 17:59
uber Mouse!
Megaloria
13-12-2005, 18:03
We all know where this is going to take us.

http://bmfm.8m.net/2006BMFM.jpg
Revasser
13-12-2005, 18:05
I doubt it would happen, as it's the structure of the brain that corresponds to intelligence, not the nature of the neurones. Besides, most univeristy ethic boards have procedures in place to deal with part-human chimeras (the guidance is usually 'destroy it the moment it shows signs of greater intelligence').

Gee, isn't that nice of them.

"Sweet Jesus, that mouse is using a calculator! We can't let this madness spread... KILL THE MICE!"
Gauthier
13-12-2005, 18:10
Gee, isn't that nice of them.

"Sweet Jesus, that mouse is using a calculator! We can't let this madness spread... KILL THE MICE!"

By then the mice would have turned the lab into a Cube-style deathtrap .
Revasser
13-12-2005, 18:16
By then the mice would have turned the lab into a Cube-style deathtrap .

I, for one, welcome our new super-intelligent, mouse-human Chimera overlords.
Anybodybutbushia
13-12-2005, 18:22
We will make great pets.