This is really interesting...anyone got a reason?
Serapindal
31-10-2005, 04:10
My hair started greying when I was 10...
:confused:
Kreitzmoorland
31-10-2005, 04:11
My hair started greying when I was 10...
:confused:Your hair follicles just stoped producing a pigment protein (melanin) a little earlier than normal. no big deal; its probably genetic.
Heron-Marked Warriors
31-10-2005, 04:12
Reason: shit happens
Neo Kervoskia
31-10-2005, 04:12
You have the herpes.
Rotovia-
31-10-2005, 04:13
Your hair follicles just stoped producing a pigment protein (melanin) a little earlier than normal. no big deal; its probably genetic.
Beat me to it.
Nothing to worry about. Mine did the same. My trick is to yank the hairs out as they come through. Which isn't a problem 'cos I seem to have hair to spare.
Serapindal
31-10-2005, 04:14
Your hair follicles just stoped producing a pigment protein (melanin) a little earlier than normal. no big deal; its probably genetic.
My parents still don't have white hair. My grandfather's started greying when he was 65. >_<
Rotovia-
31-10-2005, 04:14
You have the herpes.
And cancer. You probally got it from swimming in the same pool as a boy/girl without wearing underwear under your swimmers.
H N Fiddlebottoms VIII
31-10-2005, 04:25
And cancer. You probally got it from swimming in the same pool as a boy/girl without wearing underwear under your swimmers.
Or he rode the New York subway system. Everytime I enter one of those terminals I can feel my time of death approaching by about 12 minutes, and yet I have no money for a cab.
Bad genes my friend, bad genes...
Kreitzmoorland
31-10-2005, 04:32
My parents still don't have white hair. My grandfather's started greying when he was 65. >_<It's probably a recessive trait. Or maybe a mutation, but I doubt it. But anyway, I went to school with a few kids who had grey hairs since grade school. Its not all that uncommon.
I'm taking a look in a couple medical journals.
EDIT: well, I can't find anything very applicable.This was a study of various acids on follicle growth and health, but I don't think it will help you much. Its prettytechnical for a normal person to understand, anyway. I'n sticking woth the genetic argument. it is theoretically possible that some environmental factor has inhibited a pigment-producing metabolic pathway, but I think that's unlikely.
Towards dissecting the pathogenesis of retinoid-induced hair loss: all-trans retinoic acid induces premature hair follicle regression (catagen) by upregulation of transforming growth factor-beta2 in the dermal papilla.
Foitzik K, Spexard T, Nakamura M, Halsner U, Paus R.
Department of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
Diffuse hair loss ranks among the most frequent and psychologically most distressing adverse effects of systemic therapy with retinoids, which severely limits their therapeutic use even where clinically desired. Since the underlying mechanisms of retinoid-induced effluvium are as yet unknown, we have investigated the influence of the prototypic retinoid all-trans retinoic acid (ATRA, tretinoin) on the growth of human scalp hair follicles (HF) in culture. HF in the anagen VI stage of the hair cycle were cultured in the presence of 10(-8) or 10(-10) M ATRA. Compared with controls, hair shaft elongation declined significantly already after 2 d in the ATRA-treated group, and approximately 80% of the ATRA-treated HF had prematurely entered catagen-like stage at day 6, compared with 30% in the control group. This corresponded to an upregulation of apoptotic and a downregulation of Ki67-positive cells in ATRA-treated HF. Since transforming growth factor (TGF)-beta has been implicated as a key inducer of catagen, we next studied whether ATRA treatment had any effect on follicular expression. TGF-beta2 immunoreactivity was detected in the outer root sheath of anagen VI scalp HF. In catagen follicles, TGF-beta2 was also expressed in the regressing epithelial strand. After 4 d of ATRA treatment, TGF-beta2 was significantly upregulated in anagen HF in the dermal papilla (DP) and the dermal sheath, 7, and TGF-beta neutralizing antibody partially abrogated at RA induced hair growth inhibition. Real-time PCR confirmed a significant upregulation of TGF-beta2 transcripts in ATRA-treated hair bulbs. This study is the first to provide direct evidence that ATRA can indeed induce a catagen-like stage in human HF and suggests that this occurs, at least in part, via upregulation of TGF-beta2 in the DP. Therefore, topical TGF-beta2/TGF-beta receptor II antagonists deserve to be explored for the prevention and management of retinoid-induced hair loss.
Hobbesianland
31-10-2005, 04:50
I knew a kid with a huge bald spot, happened when he was only 11. A few grey hairs... could be worse! ;)
My hair started greying when I was 10...
:confused:
Obviously the fault actually lies with yourself in general. Perhaps you were just born a horrible person by nature, and now your hair shows signs of worthlessness as well? Just an hypothesis.
Biotopia
31-10-2005, 05:24
that's cool! I know a couple of guys with bald spots/thinning hair and i'm only 19
Neu Leonstein
31-10-2005, 05:26
Department of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, Germany.
So they're doing something afterall...who would've thought.